Tutorials

We will show you the main functions of sccross with the matched mouse cortex dataset experiments.

• Matched mouse cortex data expeirment
  • Step 1: Data preprocessing
    • Preprocess scRNA-seq data
    • Preprocess scATAC-seq data
    • Prepare atac data’s gene activity score
    • Save preprocessed data files
  • Step2: Model traning
    • Config dataset
    • Config MNN prior
    • Train model
  • Step3: Single cell multi-omics integration
  • Step4: Single cell multi-omics cross modality generation
  • Step5: Single cell omics data self augmentation
  • Step6: Single cell multi-omics matched simulation
  • Step7: Single cell multi-omics in-silico perturbation
    • Identify genes’ differential expression between cell clusters with in-silico perturbation
    • Maintain in-silico perturbation while cross generation